Apolipoprotein A1 -75 G/A and +83 C/T polymorphisms and renal cancer risk

(ct/ga)n polymorphisms of gata3 gene and risk of breast cancer

Apolipoprotein A1 polymorphisms and risk of coronary artery disease: a meta-analysis

INTRODUCTION It has been reported that APOA1 -75G/A polymorphism might be associated with susceptibility to coronary artery disease (CAD). Owing to mixed and inconclusive results, we conducted a meta-analysis to systematically summarize and clarify the association between APOA1-75G/A polymorphism and the risk of CAD. MATERIAL AND METHODS A systematic search of studies on the association of si...

Effect of apolipoprotein A1 genetic polymorphisms on lipid profiles and the risk of coronary artery disease

BACKGROUND The disorder of lipid metabolism and genetic predisposition are major risk factors for coronary artery disease (CAD). Variants in the apolipoprotein A1 (APOA1) gene play an important role in the regulation of lipids. The objective of the present study was to investigate the effect of two polymorphisms (-75 G/A and +83 C/T) of APOA1 on lipid profiles and the risk of CAD. METHODS A t...

The association between small dense low density lipoprotein,apolipoprotein B, apolipoprotein B/apolipoprotein A1 ratio and coronary artery stenosis

  Abstract   Background: Recently, small dense low density lipoprotein (sdLDL) has been   highlighted as a new risk factor for the coronary artery disease (CAD).Small dense   LDLs are believed to be atherogenic since these particles are taken up more easily by   arterial wall. They are readily oxidized and have reduced affinity for low density   lipoprotein (LDL) receptor and increased affinity...

Apolipoprotein E polymorphisms and risk of malaria.

N those associated with haemoglobinopathies N those within the major histocompatibility complex (HMC), including HLA class I and class II and the tumour necrosis factor promoter N those within genes not associated with HMC, such as ICAM-1, CD36, and possibly the gene for nitric oxide synthase N probably the gene for apolipoprotein E (APOE), as our recent data suggest, and upon which we comment ...